Hemophilia (Bleeder՚s Disease, Disease of the Hapsburg, the Disease of Kings) - Diseases Involving Specific Blood Factors

• Hemophilia is a blood disease with a long and interesting history.
• It is characterized by a prolonged coagulation time and hemorrhagic tendencies.
• The disease is hereditary, the defect being carried by the X chromosome, and is transmitted as a gender-linked Mendelian recessive trait; thus hemophilia occurs only in males, but is transmitted through an unaffected daughter to a grandson.
• The sons of a hemophiliac are normal and are not carriers of the trait; the heterozygous daughters carry …

… (1019 more words, 1 figure) …